Background:

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Applications:

ELISA, WB, IHC

Name of antibody:

MAP3K2

Immunogen:

Synthetic peptide of human MAP3K2

Full name:

mitogen-activated protein kinase kinase kinase 2

Synonyms：

MEKK2; MEKK2B

SwissProt:

Q9Y2U5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer and human gastric cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

70 kDa

WB Positive control:

231 and Hepg2 cell

WB Recommended dilution:

200-1000